|
KMID : 0370220040480030182
|
|
Yakhak Hoeji
2004 Volume.48 No. 3 p.182 ~ p.188
|
|
|
Design and Synthesis of Anticonvulsive Agents as Potential Dual Acting Prodrugs and Their Anticonvulsive Activities
|
|
김은경/Kim EK
최병기/김종걸/이정희/최종원/이응석/Choi BK/Kim JG/Lee JH/Choi JW/Lee ES
|
|
|
Abstract
|
|
|
|
This study aimed to synthesize new anticonvulsive agents as potential dual acting prodrugs. For the synthesis of ester or amide prodrug types, p- hydroxybenzaldehyde or valproic acid was coupled with clinically usable anticonvulsants or GABAmimetics with use of DCC/DMAP coupling methods. Also their anticonvulsive activities were evaluated.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|